After activating Jetpack for WordPress plugin, a line of HTML code is added to every web pages of the WordPress website to call a JavaScript named devicepx-jetpack.js. The line of HTML code looks like the following:

https://s0.wp.com/wp-content/js/devicepx-jetpack.js?ver=YYYYMM

JS functions in devicepx-jetpack.js is used to manage image replacements on devices that have HiDPI (High DPI) and Retina display. However, devicepx-jetpack.js gets loaded even though you don’t use any of the Jetpack features, i.e. when you deactivate all Jetpack features but left plugin activated.

It’s possible to remove the loading of devicepx-jetpack.js, by adding the following code snippet into the active theme’s functions.php file:

function tj_dequeue_devicepx() {
    wp_dequeue_script( 'devicepx' );
}
add_action( 'wp_enqueue_scripts', 'tj_dequeue_devicepx' );